Buckminster fuller died
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Solving neurodegeneration: common mechanisms and strategies for new treatments
Etiological features of neurodegenerative disorders
Alzheimer’s disease and related dementias
The symptoms associated with neurodegenerative disease are largely dependent on the CNS tissue affected, which varies across diseases such as Alzheimer’s Disease (AD), Huntington’s Disease (HD), Parkinson’s Disease (PD), and Amyotrophic lateral sclerosis (ALS). Although each neurodegenerative disease is distinct in terms of etiology, severity, and rate of progression, shared molecular changes and mechanisms can be identified offering potential avenues for research across multiple diseases.
Alzheimer’s Disease represents the most common form of dementia, predominantly afflicting the aged population [3]. Over time, patients develop gradual but progressive memory loss and cognitive decline associated with the degeneration of neurons [4]. In AD, severity of symptoms is correlated with pathophysiological events caused by protein aggregations in the cerebral cortex [5,6,7,8]. These have been shown histologically
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Buckminster Fuller
American philosopher, architect and inventor (1895–1983)
Richard Buckminster Fuller (; July 12, 1895 – July 1, 1983)[1] was an American architect, systems theorist, writer, designer, inventor, philosopher, and futurist. He styled his name as R. Buckminster Fuller in his writings, publishing more than 30 books and coining or popularizing such terms as "Spaceship Earth", "Dymaxion" (e.g., Dymaxion house, Dymaxion car, Dymaxion map), "ephemeralization", "synergetics", and "tensegrity".
Fuller developed numerous inventions, mainly architectural designs, and popularized the widely known geodesic dome; carbon molecules known as fullerenes were later named by scientists for their structural and mathematical resemblance to geodesic spheres. He also served as the second World President of Mensa International from 1974 to 1983.[2][3]
Fuller was awarded 28 United States patents[4] and many honorary doctorates. In 1960, he was awarded the Frank P. Brown Medal from The Franklin Institute. He was elected an honorary memb
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Published in final edited form as: Cell Rep. 2024 Apr 17;43(5):114102. doi: 10.1016/j.celrep.2024.114102
Ryo Terao
1John F. Hardesty, MD Department of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA
2Department of Ophthalmology, Graduate School of Medicine, the University of Tokyo, Tokyo, Japan
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Tae Jun Lee
1John F. Hardesty, MD Department of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA
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Jason Colasanti
1John F. Hardesty, MD Department of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA
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Charles W Pfeifer
1John F. Hardesty, MD Department of Ophthalmology & Visual Sciences, Washington University School of Medicine, St. Louis, MO, USA
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